Black pill
The black pill represents nihilism to those on the extreme right -- a realization that the system is too far gone to change, and the powers that govern our lives are too deeply entrenched and too powerful.
In the incel movement, a "Blackpilled" male believes that no matter what he does to improve himself, he will never find a romantic and/or sexual partner, and he is doomed to a life of unhappiness and rejection.